Ingredient Science

RYVA redefines nutrient delivery through molecular precision.

What's in the strip. Why It's There. Where It Comes From.

Transparency isn't a buzzword; it's our clinical mandate. Every milligram in RYVA strips is selected for bioavailability, ethical sourcing, and proven efficacy.

REST

Valerian Root · Lavender · Chamomile · Hibiscus · Melatonin

Melatonin

Mechanism

Hormone produced by the pineal gland in response to darkness. Supplemental melatonin signals the circadian clock to initiate sleep onset. Reduces sleep onset latency without dependency risk. Does not induce sedation reinforces the body's natural sleep-wake rhythm.

Sourcing

Synthetic melatonin, biosynthetically equivalent to endogenous production. Pharmaceutical-grade. Dosed at physiologically relevant levels not the excessive amounts common in gummies.

Valerian Root Extract

Mechanism

Contains valerenic acid and isovaleric acid, believed to interact with GABA receptors similarly to pharmaceutical anxiolytics but through a milder, non-dependency-forming mechanism. Used for over 2,000 years in European herbalism for relaxation and sleep quality.

Sourcing

Standardized Valeriana officinalis extract. Consistent active compound profile. Extensive history in European pharmacopoeia traditions with a strong safety record.

Lavender Extract

Mechanism

Contains linalool and linalyl acetate — aromatic compounds with documented anxiolytic properties. When delivered systemically, lavender extract reduces nervous system excitability and supports sleep onset. Works synergistically with other GABAergic botanicals.

Sourcing

Extracted from Lavandula angustifolia flowers. Used therapeutically in European markets (notably as the branded pharmaceutical Silexan). Standardized botanical extract for consistency.

Chamomile Extract

Mechanism

Contains apigenin — a flavonoid that binds to benzodiazepine receptors, producing mild sedative and anxiolytic effects without pharmacological risk. Also a mild anti-inflammatory. One of the longest-documented botanicals for sleep and nervous system support in Western herbal medicine.

Sourcing

Standardized Matricaria chamomilla (German chamomile) extract, normalized to apigenin content. Ancient use across Egyptian, Roman, and Greek traditions. Extensively studied in modern clinical literature.

Hibiscus Extract

Mechanism

Anthocyanins and flavonoids with antioxidant and mild adaptogenic properties. Contributes to circulatory relaxation and cortisol modulation — supporting the physiological transition from waking to rest. Complementary action to the core sleep-promoting actives in REST.

Sourcing

Hibiscus sabdariffa calyces. Used in traditional Ayurvedic, African, and Middle Eastern wellness practices. Rich in polyphenols with a strong antioxidant profile.

RISE

Green Tea Caffeine · L-Theanine · Vitamin B12

Green Tea Caffeine

Mechanism

Blocks adenosine receptors to reduce perceived fatigue and increase alertness. When paired with naturally co-occurring L-Theanine, the stimulant response is modulated: smoother onset, less aggressive peak, significantly reduced post-caffeine energy drop. Functionally cleaner than anhydrous caffeine.

Sourcing

Extracted from Camellia sinensis leaves. Over 4,000 years of use in Chinese and Japanese wellness traditions. The caffeine+theanine pairing in natural green tea is the basis for RISE's sustained-energy design.

L-Theanine (RISE)

Mechanism

Amino acid found almost exclusively in Camellia sinensis. Promotes alpha-wave brain activity — the neural state associated with calm, focused alertness — without drowsiness. When combined with caffeine, modulates the stimulant response: reduces jitteriness, smooths onset, extends alertness duration without increasing peak intensity.

Sourcing

Sourced from Camellia sinensis. Used in both RISE (with caffeine for focus amplification) and CALM (without caffeine for stress modulation) — demonstrating the compound's cross-SKU versatility.

Vitamin B12 (Cobalamin)

Mechanism

Essential cofactor in the conversion of carbohydrates to glucose — the primary fuel for both muscular and cognitive energy production. B12 deficiency manifests as fatigue, cognitive fog, and reduced endurance. Sublingual B12 delivery is the clinically preferred route for individuals with absorption issues.

Sourcing

Methylcobalamin or cyanocobalamin — most bioavailable forms. Sublingual B12 has clinical precedent: prescribed sublingually for pernicious anemia and B12 malabsorption. RYVA's strip format is inherently optimal for this ingredient.

REVIVE

Curcumin · Amla · Andrographis · Phyllanthus Niruri · Chicory Root

Curcuma Longa (Curcumin)

Mechanism

Inhibits NF-kB signaling — a key inflammatory pathway — and supports Phase II liver detoxification enzymes. Anti-inflammatory and antioxidant properties help the body process metabolic byproducts efficiently. Sublingual delivery significantly improves absorption of this lipophilic compound, which is notoriously poorly absorbed through the GI tract.

Sourcing

Extracted from Curcuma longa rhizomes. 4,000+ years of use in Ayurvedic medicine. Sublingual delivery in REVIVE is a meaningful formulation advantage for a compound that struggles with oral bioavailability.

Phyllanthus Emblica (Amla)

Mechanism

One of the richest natural sources of Vitamin C. Contains tannins and ellagic acid that contribute to liver and digestive wellness. Classified as a Rasayana in Ayurveda — herbs that promote longevity and systemic resilience. Antioxidant density helps neutralize oxidative stress from alcohol metabolism.

Sourcing

Sourced from Phyllanthus emblica fruit. Cornerstone of Ayurvedic medicine; one of three fruits in the classic Triphala formulation. Vitamin C content significantly higher than citrus and remains stable after processing.

Andrographis Paniculata

Mechanism

Contains andrographolides — diterpene compounds with hepatoprotective and anti-inflammatory properties. Studied for ability to support liver enzyme activity involved in detoxification. Traditionally used for recovery from overindulgence and physical stress. Known in Ayurvedic tradition as 'King of Bitters.'

Sourcing

Native to South and Southeast Asia. Used in Indian, Chinese, and Thai traditional medicine systems. Standardized extracts common in European herbal pharmacopoeias

Phyllanthus Niruri

Mechanism

Contains phyllanthin and hypophyllanthin — compounds studied for hepatoprotective activity and supporting normal liver enzyme levels. Complements Andrographis Paniculata in a traditional Ayurvedic liver-support pairing. Known as 'Stonebreaker' in Latin American folk medicine and Bhumyamalaki in Ayurveda.

Sourcing

Widely distributed across tropical regions. Used in Ayurvedic, Unani, and traditional Brazilian medicine. The Phyllanthus Niruri + Andrographis pairing in REVIVE reflects a traditional Ayurvedic formulation principle.

Cichorium Intybus (Chicory Root)

Mechanism

Contains inulin — a prebiotic fiber supporting gut microbiome diversity — and sesquiterpene lactones with anti-inflammatory and digestive-supportive properties. Contributes to digestive comfort and fluid balance, helping the body stabilize after the dehydrating and inflammatory effects of alcohol.

Sourcing

Sourced from Cichorium intybus root. Cultivated primarily in Europe and North Africa. Used historically as a liver tonic and digestive bitter in European herbal medicine.

CALM

L-Theanine · GABA · Vitamin B6

L-Theanine (CALM)

Mechanism

In CALM, L-Theanine operates without caffeine — functioning as a pure anxiolytic. At 50mg, promotes relaxed alertness without sedation — the cognitive state associated with meditation and creative flow. One of the few non-sedating compounds with documented evidence for reducing subjective stress and improving attentional performance under pressure.

Sourcing

Sourced from Camellia sinensis. RYVA uses L-Theanine in both RISE (focus amplification) and CALM (stress modulation) — the same high-purity source, two distinct formulation contexts.

GABA (Gamma-Aminobutyric Acid)

Mechanism

The brain's primary inhibitory neurotransmitter. Reduces neural excitability by counterbalancing stimulatory neurotransmitter activity. Chronic stress can compromise endogenous GABA production. At 25mg in CALM, formulated to support normal nervous system tone without impairing alertness or motor function.

Sourcing

Synthetic GABA — biosynthetically equivalent to the body's own production. Sublingual delivery is considered a superior administration route for this compound vs. oral capsules due to improved absorption through the mucosal pathway.

Vitamin B6 (Pyridoxine)

Mechanism

Cofactor in the synthesis of serotonin, dopamine, and GABA itself — a foundational nutrient for mood regulation and nervous system function. Also supports normal energy metabolism, preventing the fatigue-driven stress response that compounds anxiety. At 6mg in CALM, supports the neurochemical infrastructure needed for both relaxation and mental clarity.

Sourcing

Delivered as pyridoxine HCl, the standard supplemental form. Recognized in clinical nutrition for its role in neurotransmitter metabolism. Inclusion in CALM reflects RYVA's approach to full-spectrum formulation — targeting underlying biochemistry, not just symptoms.

SPARK

Cordyceps Militaris · Shilajit · Oyster Peptide

Cordyceps Militaris

Mechanism

Contains cordycepin and adenosine — compounds that support mitochondrial ATP production and improve oxygen utilization. Used for centuries in Tibetan and Chinese medicine to support stamina, libido, and recovery. Modern research focused on testosterone support and VO2 max in athletic populations.

Sourcing

Cultivated Cordyceps Militaris — the sustainable alternative to wild-harvested Cordyceps Sinensis (one of the most expensive natural substances on earth). Militaris contains comparable or higher concentrations of key actives including cordycepin.

Shilajit

Mechanism

Mineral-dense resinous exudate from high-altitude Himalayan rock formations. Contains fulvic acid — a bioactive compound that enhances cellular absorption of minerals and nutrients — plus 84+ trace minerals in ionic form. Studied for effects on testosterone levels, mitochondrial function, and physical stamina. One of the most complex naturally occurring wellness substances.

Sourcing

Purified Himalayan or Central Asian Shilajit resin. Raw Shilajit may contain heavy metals — purification is non-negotiable. Standardized to fulvic acid content. One of the most prized substances in Ayurvedic pharmacology.

Oyster Peptide

Mechanism

Derived from Crassostrea gigas (Pacific oyster). Concentrated source of bioactive peptides, zinc, taurine, and trace minerals. Zinc is the most critical micronutrient for male reproductive health and testosterone maintenance. Oysters contain the highest natural zinc concentration of any food source. Unique amino acid sequences with studied antioxidant and hormone-supporting properties.

Sourcing

Derived from sustainably sourced Pacific oyster. Enzymatic hydrolysis produces peptides of optimized molecular weight for superior absorption. The oyster's association with vitality has roots across Mediterranean, Japanese, and Chinese cultures. ALLERGEN: Contains shellfish (oyster). Not suitable for individuals with shellfish or seafood allergies.

GLOW

Collagen Peptides · Vitamin E

Collagen Peptides

Mechanism

Hydrolyzed short-chain amino acid sequences (primarily glycine, proline, hydroxyproline) shown to stimulate fibroblast activity and support endogenous collagen synthesis. Natural collagen production declines ~1% per year from the mid-twenties. Clinical studies demonstrate improved skin elasticity, hydration, and nail/hair structural integrity with consistent supplementation.

Sourcing

Hydrolyzed bovine or marine collagen peptides. Enzymatic hydrolysis reduces molecular weight to enhance bioavailability. Among the most well-researched areas in beauty nutrition — multiple peer-reviewed studies support effectiveness with consistent use.

Vitamin E (Tocopherol)

Mechanism

Fat-soluble antioxidant that protects cell membranes — including skin cells — from oxidative damage caused by UV exposure, pollution, and metabolic byproducts. Works synergistically with collagen: while peptides support structural regeneration, Vitamin E protects existing collagen from free radical degradation. Also supports healthy lipid metabolism and immune function.

Sourcing

Delivered as d-alpha-tocopherol (natural form, superior bioavailability). Fat-soluble compounds like Vitamin E benefit from RYVA's MCT-containing strip matrix, which aids absorption of lipophilic actives.

CURB

Saffron Extract · Chromium · Molybdenum

Saffron Extract (Crocus Sativus)

Mechanism

Contains safranal and crocin — compounds that modulate serotonin reuptake in a mechanism similar (but gentler) to pharmaceutical SSRIs. Clinical studies show saffron extract reduces compulsive snacking and emotional eating by supporting serotonin availability — the neurotransmitter most directly linked to satiety and mood stability.

Sourcing

Standardized Crocus sativus extract, normalized to safranal content. Saffron requires 150+ flowers to produce a single gram — one of the most labor-intensive agricultural products in the world. Used in Persian, Indian, and Mediterranean medicine for over 3,500 years.

Chromium

Mechanism

Essential trace mineral that enhances insulin action — the hormone responsible for transporting glucose into cells for energy use. Supports normal macronutrient metabolism and maintains blood glucose within a healthy range, reducing glycemic fluctuations that drive carbohydrate cravings and between-meal hunger.

Sourcing

Delivered as chromium picolinate — most bioavailable and extensively studied chromium form. Picolinate chelation significantly enhances absorption vs. other chromium salts. Recognized by the European Food Safety Authority for contribution to normal macronutrient metabolism.

Molybdenum

Mechanism

Essential trace mineral and cofactor for sulfite oxidase, xanthine oxidase, and aldehyde oxidase — enzymes responsible for processing sulfur-containing amino acids, purines, and certain dietary toxins. Adequate molybdenum status ensures metabolic pathways run cleanly, supporting liver function, amino acid metabolism, and natural detoxification capacity.

Sourcing

Delivered as sodium molybdate or ammonium molybdate. Recognized as an essential nutrient by all major health authorities. Deficiency linked to impaired sulfur amino acid metabolism. Often overlooked in supplement formulations — CURB addresses a foundational metabolic gap.

EDGE

Lion's Mane · Maitake · Cordyceps Sinensis · Shiitake

Lion's Mane (Hericium Erinaceus) — 30mg

Mechanism

Contains hericenones (fruiting body) and erinacines (mycelium) — compounds studied for stimulating Nerve Growth Factor (NGF) synthesis. NGF plays a critical role in the growth, maintenance, and survival of neurons. Significant academic interest for neuroplasticity support and maintaining neural infrastructure underlying memory, learning, and focus. Over 1,000 years of use in Chinese and Japanese medicine.

Sourcing

Fruiting body extract, standardized to beta-glucan content. Fruiting body preferred over mycelium-only products, which may contain significant starch filler. EDGE uses 30mg — the highest individual dose in the mushroom complex.

Cordyceps Sinensis (EDGE) — 25mg

Mechanism

In EDGE, formulated for cognitive-physical synergy — sustained energy metabolism and oxygen utilization that keeps mind and body operating at the same level during extended focus demands. Cordycepin and adenosine compounds support mitochondrial efficiency. Used in Traditional Chinese Medicine for over 1,500 years as a Qi tonic.

Sourcing

Cultivated Cordyceps Sinensis extract. Wild Cordyceps Sinensis (harvested from Tibetan Plateau) exceeds $20,000/kg. Cultivated form provides comparable active compound profiles at accessible price points.

Maitake (Grifola Frondosa) — 25mg

Mechanism

Contains beta-1,3/1,6-glucans with well-documented immune-modulating properties. Contributes adaptogenic support in EDGE — helping the body maintain homeostasis under cognitive and physical stress. Also contains the D-fraction polysaccharide studied for immune cell activity and antioxidant defense.

Sourcing

Cultivated Grifola frondosa. Standard in Japanese and Chinese culinary and medicinal traditions. One of the few mushrooms with significant presence in both Eastern medicine and Western culinary culture — lending credibility to its safety profile.

Shiitake (Lentinus Edodes) — 20mg

Mechanism

Contains lentinan (beta-glucan polysaccharide), eritadenine (supports healthy cholesterol metabolism), and a range of B vitamins. In EDGE, contributes antioxidant and immune-supportive properties complementary to the cognitive and energy-focused actives.

Sourcing

Second-longest history of medicinal mushroom use, behind only Reishi. Cultivated Lentinus edodes. Extensively studied in Japanese oncology and immunology research for lentinan content. Globally cultivated; one of the most widely consumed medicinal mushrooms worldwide

Scientist working at a lab desk with computer and various lab equipment.

The Bioavailability Advantage

All RYVA products are manufactured in FDA-registered, cGMP-compliant facilities. Third-party lab testing for purity and potency is available on request.